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Top of web page Study description Study style Arms and also Interventions Outcome measures Eligibility Criteria Contacts and also Locations more Information
Recent literature data suggest advantageous effects that dietary fats in patients v cancers, in details polyunsaturated fatty acids (PUFAs). Fish oil and evening primrose oil administer a high quantity of PUFAs and a desirable n-6/n-3 PUFAs ratio.

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condition or an illness Intervention/treatment step
breast Cancer dietary Supplement: Fish oil + EPO not Applicable

Breast cancer (BC) is top cancer in women. As most of the cancers, that is characterized by inflammation and also alternations in lipid and fatty acid metabolism. Patients through BC have impaired fatty mountain profiles, short level of PUFAs, and also high n-6/n-3 PUFAs ratio. Moreover, these transforms are concerned clinical outcome.

Fish oil is the richest resource of anti-inflammatory n-3 PUFAs. Evening primrose oil (EPO) is wealthy in 18:3 n-6, the only n-6 fat acid v an anti-inflammatory effect. Diet intake of fish oil or EPO has actually been shown to diminish inflammation and improve PUFAs condition in patients through cancers. However, the is not recognized what is the result of linked EPO and also fish oil in BC patients.

The study style is double-blind, controlled, randomized nutritional intervention. The participants room randomly assigned right into intervention and also control team before beginning chemotherapy. Every patients obtain nutritional counseling to attain a day-to-day energy and protein intake follow to recommended dietary allowances, through (intervention) or there is no (control) the milled seed mix.

Top of web page Study summary Study architecture Arms and also Interventions Outcome actions Eligibility Criteria Contacts and Locations more Information

Layout table for study details
Study kind : Interventional (Clinical Trial)
EstimatedEnrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention design Description: This study is a parallel, randomized, dual blind, controlled, 3-months supplementation, investigate health results of diet intake the fish oil and EPO, in patients through breast cancer undergoing chemotherapy.

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At the start of the study, every patients obtained nutritional counseling, where half of the study subjects are randomly assigned to a treatment arm through fish oil and EPO, or control arm through mineral oil together placebo. Treatment arm is listed with 2 gelatin capsules the fish oil and 3 gel capsules of EPO (400 mg eicosapentaenoic acid, 600 mg docosahexaenoic acid and 351 mg gamma-linolenic acid). Manage arm will certainly consume 5 gel capsules the 1g of mineral oil.

Masking: Triple (Participant, Investigator, Outcomes Assessor)
Masking Description: dual blind
Primary Purpose: straightforward Science
Official Title: Fish Oil and also Evening Primrose Oil in the treatment of breast Cancer
Actual research Start day : February 20, 2019
approximated Primary Completion date : December 20, 2022
estimated Study Completion day : June 20, 2023